We already knew Megan Fox was hosting Saturday Night Live’s Sept. 26 season premiere, with musical guest U2, but NBC has also announced the host/musical guest line-up for three more SNL installments.

Week two (Oct. 3) host is Ryan Reynolds, with Lady Gaga as musical guest; week three (Oct. 10) is host Drew Barrymore with singer Regina Spektor; and week four (Oct. 17) will be hosted by Gerard Butler, with musical guest Shakira.

It’ll be the first time hosting for Fox, Reynolds and Butler, and the sixth time for Barrymore, who first hosted SNL in 1982, when she was seven-years-old and Squeeze was the musical guest.

Barrymore, in addition to holding the record as youngest SNL host ever, also becomes the first female to ever host the show six times. Cool.

Below, the complete press release from NBC:

NBC’S SATURDAY NIGHT LIVE PREMIERES SEPTEMBER 26 WITH ACTRESS MEGAN FOX & GRAMMY AWARD-WINNING MUSICAL GUEST U2

SNL Kicks Off 35th Season With Live Shows on Four Consecutive Weeks

UPCOMING SHOWS: October 3 – Ryan Reynolds/ Lady Gaga; October 10 – Drew Barrymore/ Regina Spektor; October 17 – Gerard Butler/ Shakira

New York, NY – September 10, 2009 – Saturday Night Live, NBC’s Emmy Award-winning late-night comedy showcase, enters its 35th season on Saturday, September 26 for another year of laughs, surprises and great performances. SNL premieres with one of Hollywood’s most sought-after stars, Megan Fox, and Grammy award-winning musical guest U2.
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